Ugi reaction

From Biocrawler, the free encyclopedia.

The Ugi reaction is a multi component reaction in organic chemistry involving a ketone or aldehyde, an amine, a isocyanide and a carboxylic acid to form a bis-amide.

The chemistry is related to the Passerini reaction and belongs to the class of nucleophilic addition reactions.

References

The Passerini Reaction L. Banfi, R.Riva in Organic Reactions vol. 65 L.E. Overman Ed. Wiley 2005 ISNB 0-471-68260-8

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