Triflate

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Triflate, more formally known as trifluoromethanesulfonate, has the structure CF₃SO₃^-. It is an extremely stable polyatomic ion, being the conjugate base of triflic acid (CF₃SO₃H), one of the strongest acids known and a super acid.

A triflate It is an excellent leaving group used in certain organic reactions such as nucleophilic substitution, Suzuki couplings and Heck reactions. For example, in an alkyl triflate such as n-butyl triflate, (CH₃CH₂CH₂OTf), the "OTf" is used to designate the triflate leaving group. Since alkyl triflates are extremely reactive in SN2 reactions, they must be stored in conditions free of nucleophiles (e.g. water).

Tf represents the trifyl group, CF₃SO₂^-.

Wikipedia (http://en.wikipedia.org/wiki/Main_Page) Triflate (http://en.wikipedia.org/wiki/Triflate) version history (http://en.wikipedia.org/w/index.php?title=Triflate&action=history) GNU Free Documentation Lizenz (http://en.wikipedia.org/wiki/Wikipedia:Text_of_the_GNU_Free_Documentation_License) CC-by-sa (http://creativecommons.org/licenses/by-sa/2.5/)

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