Succinyl-CoA
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Succinyl-CoA (coenzyme A is grey)
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Source
It is an important intermediate in the citric acid cycle, where is it synthetised from α-Ketoglutarate by α-ketoglutarate dehydrogenase through decarboxylation. During the process, coenzyme A is added.
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Fate
It is converted into succinate through the hydrolytic release of coenzyme A by succinyl-CoA synthetase.
Another fate of succinyl-CoA is porphyrin synthesis, where succinyl-CoA and glycine are combined by ALA synthase to form δ-aminolevulinic acid (dALA).
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