Pharmacogenomics
From Biocrawler, the free encyclopedia.
Pharmacogenomics is the branch of pharmaceutics which deals with the influence of genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with a drug's efficacy or toxicity. By doing so, pharmacogenomics aims to develop rational means to optimise drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Such approaches promise the advent of "personalized Medicine", in which drugs and drug combinations are optimized for each individual's unique genetic makeup.
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Internal links
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External links
- NCBI Primer on Pharmacogenomics (http://www.ncbi.nlm.nih.gov/About/primer/pharm.html), a quick introduction to the promise of customized drugs.
- Pharmacogenomics: Drugs Designed for You (http://gslc.genetics.utah.edu/units/pharma/), an accessible and comprehensive look at pharmacogenomics research, from the University of Utah's Genetic Science Learning Center
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