Myelofibrosis
From Biocrawler, the free encyclopedia.
Myelofibrosis is the gradual replacement of the bone marrow by connective tissue. Its main feature is "extramedullary hematopoeisis", i.e. the blood-forming cells migrate to other sites in the body, e.g. the liver or spleen. Typically affects patients > 50 years. Patients will typically have hepatosplenomegaly, and the blood smear will show "teardrop cells".
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| Health science - Medicine - Hematology |
| Hematological malignancy and White blood cells |
| Leukemia (ALL, AML, CLL, CML) - Lymphoma (Hodgkin's disease, NHL) - Multiple myeloma - MDS - Myelofibrosis - Myeloproliferative disease (Essential thrombocytosis, Polycythemia) - Neutropenia |
| Red blood cells |
| Anemia - Hemochromatosis - Sickle-cell anemia - Thalassemia - G6PD - other hemoglobinopathies |
| Coagulation and Platelets |
| Thrombosis - Deep venous thrombosis - Pulmonary embolism - Hemophilia - ITP - TTP |
