Greg Winter
From Biocrawler, the free encyclopedia.
Sir Greg Winter is a British pioneer of therapeutic monoclonal antibodies. He invented techniques to both humanise (1986) and, later, to fully-humanise, antibodies for therapeutic uses.
Prior to this groundbreaking work antibodies had failed to live up to their potential because they had been derived from mice. In 1989 Winter was a founder of Cambridge Antibody Technologies (http://www.cambridgeantibody.com), which was one of the early commercial biotech companies involved in antibody engineering.
In 2000 Winter founded a company called Domantis (http://www.domantis.com) to pioneer the use of domain antibodies, which use only the active portion of a full-sized antibody. In 1995 Winter won the King Faisal International Prize for Medicine (Molecular Immunology). Winter is currently the Joint Head of the Division of Protein and Nucleic Acid Chemistry-Biotechnology at Cambridges' Laboratory of Molecular Biology, an institution funded by the UK Medical Research Council. He is also Deputy Director of the MRC’s Centre for Protein Engineering. Winter was knighted in 2004.
