Dopamine receptor
From Biocrawler, the free encyclopedia.
The dopamine receptors are a class of G-protein coupled receptors with dopamine as their endogenous ligand.
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D1 receptor
The D1 receptor is coupled to adenylate cyclase via a stimulatory G protein
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D2 receptor
The D2 receptor is negatively coupled to adenylate cyclase via an inhibitory G protein
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D3 receptor
The D3 receptor is negatively coupled to adenylate cyclase via an inhibitory G protein
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D4 receptor
The D4 receptor is negatively coupled to adenylate cyclase via an inhibitory G protein
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D5 receptor
The D5 receptor is coupled to adenylate cyclase via a stimulatory G protein
The D1 and D5 receptors are members of the D1-like family of dopamine receptors whereas the D2, D3 and D4 receptors are members of the D2-like family.
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