BFGF
From Biocrawler, the free encyclopedia.
Member of the Fibroblast Growth Factor familly.
In normal tissue, bFGF is present in basement membranes and in the subendothelial extracellular matrix of blood vessels, and stays membrane-bound as long as there is no signal peptide.
In particular, it has been hypothesized that, during both wound healing of normal tissues and tumor development, the action of heparan sulfate degrading enzymes activates bFGF, thus mediating the formation of new blood vessels.
