Acyloin condensation
From Biocrawler, the free encyclopedia.
In chemistry, the acyloin condensation is a reductive coupling of two carboxylic esters using metallic sodium to give an α-hydroxyketone, also known as an acyloin.
The reaction is most successful when R is aliphatic and inert, high-boiling solvents such as benzene and toluene are used.
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References
- Bouveault, L.; Loquin, R. Compt. Rend. 1905, 140, 1593.
- Finley, K. T. Chem. Rev. 1964, 64, 573.
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See also
