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5q- syndrome

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5Q- syndrome is a rare disorder caused by loss of part of the long arm (Q arm) of human chromosome 5. This syndrome affects myeloid (bone marrow) cells, causing treatment-resistant anemia, and myelodysplastic syndromes that may lead to acute myelogenous leukemia.

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Reference

  • OMIM 153550 (http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=153550)
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